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Beckman Coulter

Beckman Coulter B63285 Access TSH Calibrator (3rd IS) S0-S5

Article #: B63285 TEST NAME: Thyroid Stimulating Hormone (TSH)
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1 × 2.5 mL
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Product Description

Beckman Coulter B63285 Access TSH Calibrator (3rd IS) S0-S5, Thyroid Stimulating Hormone Test (TSH Test) Specifications: Brand: Access Manufacturer: Beckman Coulter B63285 Country of Origin: United States Application: Access TSH Calibrator Container Type: Vial Test Name: Thyroid Stimulating Hormone Test (TSH Test) Test Type: Thyroid / Metabolic Assay Volume: 1 X 2.5 mL Data Sheet Related Products Beckman Coulter B63284 Access TSH Stimulating Hormone (3rd IS) 2 x 100 Determinations Beckman Coulter B63285 Access TSH Calibrator (3rd IS) S0-S5, Thyroid Stimulating Hormone Test (TSH Test) INTENDED USE: The Access-TSH (3rd IS) Calibrators are intended to calibrate the Access-TSH (3rd IS) assay for the quantitative determination of human thyroid-stimulating hormone (thyrotropin, TSH, hTSH) levels in human serum and plasma using the Access Immunoassay Systems. Beckman Coulter B63285 Access TSH Calibrator (3rd IS) S0-S5, Thyroid Stimulating Hormone Test (TSH Test) SUMMARY AND EXPLANATION: Quantitative assay calibration is the process by which samples with known analyte concentrations (i.e., assay calibrators) are tested like patient samples to measure the response. The mathematical relationship between the measured responses and the known analyte concentrations establishes the calibration curve. This mathematical relationship, or the Access TSH calibration curve, is used to convert RLU (Relative Light Unit) measurements of patient samples to specific quantitative analyte concentrations. What is  thyroid stimulating hormone test (TSH Test)? Definition: TSH is a test that measures the amount of the hormone TSH in the blood. Alternative Names: Thyrotropin; Thyroid stimulating hormone How the thyroid stimulating hormone test (TSH Test) is performed: Adult or child: Blood is drawn from a vein, usually from the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and a tourniquet is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the tourniquet to fill with blood. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. The tourniquet is then removed to restore circulation. After blood has been collected the needle is removed, and the puncture site is covered to stop any bleeding. Infant or young child: The area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. A bandage may be applied to the puncture site if there is any bleeding. Why the thyroid stimulating hormone test (TSH Test) performed?: TSH is measured as a screening test for abnormal thyroid function (either hyperthyrodism or hypothyrodism). It is also measured to monitor treatment of these conditions. The test is also done in infertile females, to check if thyroid disease is the cause of infertility. TRH, a hormone produced in the hypothalamus, stimulates the pituitary gland to release TSH. TSH subsequently stimulates the thyroid to produce thyroid hormones, T3 and T4. These hormones feedback to the hypothalamus and pituitary to regulate the release of both TSH and TRH. In certain diseases, this regulation pathway is altered, leading to under- or over-production of thyroid hormone. When a thyroid disorder is suspected clinically, a TSH level is obtained as an initial test. thyroid stimulating hormone test (TSH Test) values: [caption id="attachment_20832" align="alignleft" width="405"] Beckman Coulter B63285 Access TSH Calibrator (3rd IS) S0-S5, Thyroid Stimulating Hormone Test (TSH Test)[/caption] TSH normal values are 0.5 to 5.0 mIU/L. Some people with a TSH value over 2.0 mIU/L, who have no signs or symptoms suggestive of an under-active thyroid, may develop hypothyroidism sometime in the future. Anyone with a TSH above 2.0 mIU/L, therefore, should be followed very closely by a doctor. Normal value ranges may vary slightly among different laboratories.       What abnormal results mean: Greater-than-normal levels may indicate: Congenital hypothyroidism (cretinism) Primary hypothyroidism TSH-dependent hyperthyroidism Thyroid hormone resistance Exposure to mice (lab workers or veternarians) Lower-than-normal levels may indicate: Hyperthyroidism TSH deficiency Medications (dopamine agnoists, glucocorticoids, somatostatin analogues, bexarotine)

Technical Specifications

Brand: Beckman Coulter
Speciality: Immunoassay
Manufacturer SKU: B63285
Compatible Analyzers: Access
Test: Thyroid Stimulating Hormone (TSH)
Common Panels: Thyroid Panel