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Reagent ensures accurate assessment of thyroid autoimmune conditions.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682009006324,"sku":"A32898","price":707.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_c1300345-22ae-455c-b08d-56c821ba109f.jpg?v=1774698400"},{"product_id":"beckman-coulter-387647-access-br-monitor-calibrator-s0-s5","title":"Beckman Coulter 387647 Access BR Monitor Calibrator (S0-S5)","description":"\u003cp\u003eIntended for calibration of breast cancer markers. 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Ensures accurate and reliable autoimmune testing.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682010087668,"sku":"ODC0028","price":414.9,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_3bb8c45d-808e-4270-8c36-dc8f77f88cbd.jpg?v=1774698413"},{"product_id":"beckman-coulter-osr61105-olympus-rf-reagent-rheumatoid-factor-reagent","title":"Beckman Coulter OSR61105 Olympus RF Reagent (Rheumatoid Factor Reagent)","description":"Beckman Coulter OSR61105 Olympus RF Reagent, Olympus Rheumatoid Factor Test (RF Test) Specifications: Manufacturer: Beckman Coulter OSR61105 Country of Origin: Japan Application: Reagent Test Method: Latex-enhanced Immunoturbidimetric Method Number of Tests: 4 X 250 Tests Test Type: Autoimmune Assay UNSPSC Code: 41116004 Test Name: Rheumatoid Factor Test (RF Test) For in vitro diagnostic use only. R1: Colorless to slightly yellow; Clear; Liquid; Odorless R2: White; Clear; Liquid; Odorless Beckman Coulter OSR61105 Olympus RF Reagent Data Sheet Related products 1.Beckman Coulter ODC0028 Olympus RF Latex Calibrator (RF Calibrator) Beckman Coulter OSR61105 Olympus RF Reagent, Olympus Rheumatoid Factor Test (RF Test):  Intended Use Beckman Coulter OSR61105 Olympus RF reagent for Rheumatoid Factor quantitative determination  in human serum and plasma on Beckman Coulter AU analyzers. Understanding Beckman Coulter OSR61105 Olympus RF Reagent, Olympus Rheumatoid Factor Test (RF Test) Rheumatoid factors (RF) are antibodies targeting antigenic determinants on the Fc fragment of IgG. While typically IgM antibodies, they may also manifest as IgG, IgA, or IgE. In studies, RF sensitivity in rheumatoid arthritis ranges from 30% in population-based studies to 70-80% in hospital-based studies, indicative of more severe disease. Higher RF titers are more specific for diagnosing rheumatoid arthritis (RA), especially in cases of rapidly progressive joint destruction or with extraarticular manifestations like subcutaneous rheumatic nodules. However, RF Test is a non-specific test, with positive results observed in 1-5% of healthy individuals at low titers and in 15-20% of elderly subjects with other chronic conditions. A negative result does not rule out RA. Moreover, around 25% of diagnosed RA patients may test negative for RF Test. Positive RF Test results are also associated with autoimmune rheumatic diseases and non-rheumatic conditions like SLE, Sjögren’s syndrome, subacute bacterial endocarditis, infectious hepatitis, chronic liver diseases, chronic active pulmonary diseases, parasitic, and viral infections. Beckman Coulter OSR61105 Olympus RF Reagent, Olympus Rheumatoid Factor Test (RF Test) Methodology Immune complexes formed in solution scatter light based on their size, shape, and concentration. Turbidimeters measure the reduction in incident light due to reflection, absorption, or scatter. In this procedure, the decrease in light intensity transmitted (increase in absorbance) through suspended particles results from immunological reactions between patient serum RF and anti-RF IgG antibodies coated on latex particles. What is a Rheumatoid Factor Test (RF Test)? [caption id=\"attachment_20841\" align=\"alignleft\" width=\"469\"] Beckman Coulter OSR61105 Olympus RF Reagent, Rheumatoid Factor Test (RF Test)[\/caption] A rheumatoid factor (RF test) looks for rheumatoid factor (RF) in a sample of your blood. Rheumatoid factors are proteins made by the immune system. Normally, your immune system makes proteins called antibodies to attack germs that could make you sick. But rheumatoid factors are antibodies that sometimes attack healthy cells and tissues in your body by mistake. When this happens, you have an autoimmune disorder. Not everyone has rheumatoid factors in their blood. And some people who have them are healthy. But if you have certain symptoms and higher levels or rheumatoid-factors, you may have an autoimmune disorder or another health problem related to high RF levels. RF testing is mostly used with other tests to help diagnose rheumatoid arthritis. Rheumatoid arthritis (RA) is a type of autoimmune disorder that damages your joints and causes pain, swelling, and stiffness. It is a chronic (long-lasting) condition that can also affect your organs and cause other symptoms. High levels of rheumatoid-factors may also be a sign of other autoimmune disorders, certain infections, and certain types of cancer. Other names: RF Blood Test What Rheumatoid Factor Test (RF Test) used for? An RF-test is often used to help diagnose rheumatoid arthritis and other autoimmune disorders. RF testing may also be used to understand how severe rheumatoid arthritis may be and whether it's likely to affect organs. An RF-test alone can't diagnose any health problems.","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682010153204,"sku":"OSR61105","price":755.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_2f25102c-0bab-42e4-a443-c61e8743c827.jpg?v=1774698416"},{"product_id":"beckman-coulter-osr6159-olympus-c3-reagent-complement-3-reagent","title":"Beckman Coulter OSR6159 Olympus C3 Reagent (Complement 3 Reagent)","description":"\u003cp\u003eIntended for measurement of complement C3 in serum. 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Ensures accurate metabolic testing.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682010284276,"sku":"OSR6121","price":267.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_851a7c05-df24-4677-ab43-03e20a388225.jpg?v=1774698422"},{"product_id":"beckman-coulter-osr6221-olympus-glucose-reagent-kit","title":"Beckman Coulter OSR6221 Olympus Glucose Reagent Kit","description":"\u003cp\u003eIntended for quantitative determination of glucose in serum or plasma. Supports diabetes monitoring and metabolic testing.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682010317044,"sku":"OSR6221","price":203.7,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_903557e9-ebed-496e-be1e-2f6f57fe3877.jpg?v=1774698424"},{"product_id":"beckman-coulter-osr6621-glucose-hexokinase-4x3755-tests","title":"Beckman Coulter OSR6621 Glucose Hexokinase, 4X3755 Tests","description":"\u003cp\u003eIntended for measurement of glucose using the hexokinase enzymatic method. Supports diabetes and metabolic monitoring.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682010349812,"sku":"OSR6621","price":2150.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_1300bbcf-4873-4f56-b8b7-f1e1d1d81b4d.jpg?v=1774698427"},{"product_id":"beckman-coulter-a48617-access-shbg-reagent-100-determinations","title":"Beckman Coulter A48617 Access SHBG Reagent, 100 Determinations","description":"Beckman Coulter A48617 Access SHBG Reagent Specifications: Brand: Access® Manufacturer: Beckman Coulter A48617 Country of Origin: United States Application: Access SHBG Reagent, Rental For Use With: For use with Access Immunoassay Systems Number of Tests: 100 Tests Test Name: SHBG - Sex Hormone Binding Globulin Test Type: Reproductive Hormone AssayINTENDED USE: Beckman Coulter A48617 Access SHBG ReagentThe Access SHBG assay is a paramagnetic particle, chemiluminescent immunoassay for the quantitative determination of Sex Hormone Binding Globulin levels in human serum and plasma using the Access Immunoassay Systems.Summary and Explanation: Beckman Coulter A48617 Access SHBG ReagentSex hormone-binding globulin (SHBG) is a glycoprotein responsible for blood transport of testosterone and estradiol. SHBG is synthesized in the liver and has a high binding affinity for 17-hydroxysteroid hormones. Less than 2% of biologically active steroids are free in the circulation with the remainder being bound mostly to SHBG and albumin. SHBG has a high binding affinity to the 17-hydroxysteroid hormones while albumin has a low binding affinity. Initially, the free portion or unbound hormone fraction was believed to be the only biologically active form. It is now recognized that the portion of hormone that is weakly bound to albumin is also available to the tissues. The free hormone plus the albumin bound portion of hormones represents the “bioavailable” hormone.The measurement of SHBG can be an important indicator of a chronic or excessive androgenic activity where clinical symptoms would seem to indicate androgen in excess, but androgen levels are normal. Elevated SHBG levels can be seen in persons with androgen insensitivities, hyperthyroidism, cirrhosis of the liver and is found in patients on oral contraceptives or antiepileptic drugs. Decreased concentrations of SHBG are often seen in men with hypothyroidism and androgen replacement therapy; where women with hirsutism, virilism, polycystic ovarian syndrome (PCOS), elevated androgen levels, obesity and acromegaly will also see a decrease in SHBG levels.SHBG production is regulated by the androgen\/estrogen balance, thyroid hormones, insulin, and dietary factors. The concentration of SHBG is increased by estrogens and decreased by androgens. Therefore, SHBG production is stimulated by estradiol and suppressed by testosterone. As a result, SHBG concentrations are higher in women versus men. Pregnant women have markedly higher SHBG serum concentrations due to their increased estrogen production.","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682010579188,"sku":"A48617","price":368.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_622b2c87-7f2a-49d5-be7f-849b43f9065f.jpg?v=1774698429"},{"product_id":"beckman-coulter-a48618-access-shbg-sex-hormone-binding-globulin","title":"Beckman Coulter A48618 Access SHBG Sex Hormone-Binding Globulin","description":"\u003cp\u003eIntended for measurement of SHBG levels. 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Ensures accurate electrolyte measurement.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011103476,"sku":"AUH1018","price":54.91,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_52928360-3c52-4472-a2a7-ecf380bbb8d3.jpg?v=1774698439"},{"product_id":"beckman-coulter-osr6189-olympus-magnesium-reagent","title":"Beckman Coulter OSR6189 Olympus Magnesium Reagent","description":"Beckman Coulter OSR6189 Olympus Magnesium Reagent (Magnesium Test) Specifications: Manufacturer: Beckman Coulter OSR6189 Country of Origin: Ireland Application: Olympus Magnesium Reagent Number of Tests: 4 X 250 Tests Sample Type: General Chemistry \/ Urine Storage Requirements: Requires Refrigeration Test Name: Magnesium Test, used with AU Analyzer Series Test Type: General Chemistry UNSPSC Code: 41116004 Beckman Coulter OSR6189 Olympus Magnesium Reagent (Magnesium Test) Data Sheet Related Products: Beckman Coulter OSR60117 Olympus Calcium Reagent, 4 x 700 Tests Beckman Coulter OSR6179 Olympus CK Reagent Creative Phosphokinase   Understanding Beckman Coulter OSR6189 Olympus Magnesium Reagent (Magnesium Test): Magnesium measurements are vital for diagnosing and treating both low (hypomagnesemia) and high (hypermagnesemia) levels of magnesium in the body. Additionally, magnesium, a crucial intracellular cation, ranks second only to potassium in concentration. While the factors regulating plasma magnesium levels are not fully understood, it's believed that the parathyroid gland may play a role. Magnesium ions activate several important enzyme systems involved in phosphate group transfer and hydrolysis. Moreover, low serum magnesium levels are associated with conditions like diabetes, alcoholism, hyperthyroidism, and liver cirrhosis, while high levels may indicate renal failure, dehydration, or severe diabetic acidosis. Beckman Coulter OSR6189 Olympus Magnesium Reagent (Magnesium Test) Methodology The Magnesium procedure employs a direct method where magnesium forms a colored complex with xylidyl blue in a strongly basic solution. Furthermore, calcium interference is effectively eliminated using glycoletherdiamine-N,N,N',N'-tetraacetic acid (GEDTA). The resulting color is measured bichromatically at 520\/800 nm, with intensity directly proportional to the magnesium concentration. What is a magnesium test all about? A magnesium blood test measures the amount of magnesium in a sample of your blood. Magnesium is a mineral that you get from many kinds of foods you eat. Some examples include nuts, seeds, beans, fortified breakfast cereals, green leafy vegetables, and milk. Your body needs magnesium to help your muscles, nerves, and heart work properly. Magnesium also helps control blood pressure and blood glucose, also called blood sugar. It's important for building strong bones, and it supports your immune system. Magnesium is a type of electrolyte. Electrolytes are electrically charged minerals. They help control the amount of fluid and the balance of acids and bases (pH balance) in your body. Most of your body's magnesium is stored in your bones, organs, and other body tissue. Only a small amount is found in your blood. Your body tightly controls the amount of magnesium in your blood mainly through your: Kidneys. They filter extra magnesium from your blood and get rid of it through urine (pee). If your magnesium level is low, your kidneys limit the amount lost through urine. Intestines. They control how much magnesium you absorb from the foods you eat. Abnormal levels of blood magnesium can be caused by many different conditions. So, a magnesium test may be used to help diagnose a variety of disorders. Other names: Mg, Mag, Magnesium-Serum What magnesium test is used for? [caption id=\"attachment_20822\" align=\"alignleft\" width=\"441\"] Beckman Coulter OSR6189 Olympus Magnesium Reagent (Magnesium Test)[\/caption] A magnesium blood test is used to check the level of magnesium in your blood. It's done if your health care provider thinks your levels may not be normal: A low magnesium level is also called magnesium deficiency or hypomagnesemia. This condition is more common than levels that are too high. A high magnesium level is also called hypermagnesemia. This condition is uncommon. Most cases happen in people who have kidney failure.       A magnesium blood test may also be used to help find the cause of abnormal levels of other minerals, including calcium, potassium, and phosphorus. That's because magnesium plays a role in how your body absorbs these minerals.  ","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011136244,"sku":"OSR6189","price":247.7,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_fbf7857d-893d-472f-b840-cac6132dc626.jpg?v=1774698441"},{"product_id":"beckman-coulter-osr6130-lipase-reagent-enzyme-assay-lipase-4-x-65-tests","title":"Beckman Coulter OSR6130 Lipase Reagent Enzyme Assay Lipase 4 X 65 Tests","description":"\u003cp\u003eIntended for measurement of lipase activity in serum or plasma. 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About Beckman Coulter OSR6230 Olympus LIP Reagent - Olympus Lipase Reagent (Lipase Test - LIP Test) Measurements of serum lipase are used in the diagnosis and treatment of acute pancreatitis or pancreatic injury. Beckman Coulter OSR6230 Olympus LIP Reagent - Olympus Lipase Reagent (Lipase Test - LIP Test) Methodology: The lipase procedure is based on the colorimetric method of lmamura, et al. Pancreatic lipase hydrolyzes esters of long chain fatty acids from their triglycerides. The enzyme activity requires the presence of co-lipase. Diglyceride is hydrolyzed to 2-monoglyceride and fatty acid. The 2-monoglyceride is then measured by coupled enzyme reactions catalyzed by monoglyceride lipase (MGLP), glycerol kinase (GK), glycerol phosphate oxidase (GPO) and peroxidase (POD). What is lipase Test (Olympus LIP Test) A lipase test (LIP Test) is a blood test that measures the level of a digestive enzyme called lipase in your blood. It may also be referred to as a serum lipase or LPS. Lipase is a type of digestive enzyme that helps your body absorb fats. The pancreas -- a long, flat organ between your stomach and spine -- makes most of the lipase in your body. Your salivary, or spit, glands and your stomach also make some. Your blood normally contains some lipase. It may contain more than usual if you have a problem with your pancreas. Your doctor may want to find out the level of this protein in your blood to find how your pancreas is doing. What is lipase Test (Olympus LIP Test) used for? [caption id=\"attachment_20843\" align=\"alignleft\" width=\"419\"] Beckman Coulter OSR6230 Olympus LIP Reagent - Olympus Lipase Reagent (Lipase Test - LIP Test)[\/caption] Your doctor will order a lipase test (LIP Test) if they think you may have something wrong with your pancreas. Acute pancreatitis, which is sudden, severe inflammation of the pancreas, is the most common problem that a lipase test might be used to diagnose. If you have pancreatitis, you might have these symptoms:         Severe pain in your belly that may extend to your chest or back Belly pain that feels worse after eating Fever Loss of appetite Nausea Vomiting Fat in your stool (poop) A rapid pulse Unexplained weight loss Yellowing of your eyes and skin (jaundice) A lipase test (LIP Test) may be used to monitor your pancreas if you’ve already been diagnosed with acute or chronic (ongoing) pancreatitis. It can find out whether your blood lipase levels are increasing or decreasing. It can also be used to find out whether your treatment is working well. Sometimes, your doctor will order a lipase test (LIP Test) to help monitor or diagnose other conditions, such as: Cystic fibrosis Crohn’s disease (inflammation of your digestive tract) Celiac disease (an abnormal immune response to the protein gluten) Lipase Test (Olympus LIP Test) Results Your doctor will be looking for signs of abnormal lipase levels -- either high or low -- in your blood. The lab will provide your results on a spectrum that includes what are considered normal ranges. Normal lipase test (Olympus LIP Test) levels The normal lipase range is usually 0 to 160 units per liter (U\/L), or 0 to 2.67 microkat\/L (µkat\/L). Normal levels may vary slightly between labs, so you and your doctor will look at the ranges given with your results to figure out how your lipase levels compare. High lipase test (Olympus LIP Test) levels A high level of lipase in the blood is a sign that you may have a condition affecting the pancreas. It's likely that you have acute pancreatitis if your lipase levels are three to 10 times higher than the highest reference value. Elevated levels of lipase in your blood can also be a sign of: Pancreas diseases like a blocked duct or pancreatic cancer Chronic kidney disease Peptic ulcer (a sore in your stomach lining) Gallbladder disease Gastroenteritis (inflammation of the stomach caused by a virus) Intestinal problems, like a blocked intestine Problems with your salivary (spit) glands, such as cancer or infections Diabetes Alcohol use disorder","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011398388,"sku":"OSR6230","price":1000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_ddc8e3ae-2bbe-4fb0-b52c-c2d7338f5e21.jpg?v=1774698445"},{"product_id":"beckman-coulter-osr6122-olympus-phos-reagent-inorganic-phosphorus","title":"Beckman Coulter OSR6122 Olympus PHOS Reagent Inorganic Phosphorus","description":"\u003cp\u003eIntended for measurement of inorganic phosphorus in serum or plasma. Supports bone and renal function evaluation.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011463924,"sku":"OSR6122","price":138.3,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_440e2634-32a3-4881-9820-bc135a18af85.jpg?v=1774698448"},{"product_id":"beckman-coulter-a98856-access-25oh-vitamin-d-reagent-100-determinations","title":"Beckman Coulter A98856 Access 25OH Vitamin D Reagent, 100 Determinations","description":"Intended for quantitative 25OH Vitamin D measurement. Reagent supports nutritional and clinical evaluation.","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011496692,"sku":"A98856","price":483.9,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_a3c904b4-549b-4681-bb0f-241a18016d04.jpg?v=1774698450"},{"product_id":"beckman-coulter-a98857-access-25oh-vitamin-d-calibrator","title":"Beckman Coulter A98857 Access 25OH Vitamin D Calibrator","description":"\u003cp\u003eIntended for calibration of 25OH Vitamin D assays. Ensures accurate assessment of bone and metabolic health.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011529460,"sku":"A98857","price":242.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_80a4d109-2182-46f5-863b-4f83d9542f4b.jpg?v=1774698452"},{"product_id":"beckman-coulter-b24838-access-25-oh-vitamin-d-reagent-100-determinations","title":"Beckman Coulter B24838 Access 25 OH Vitamin D Reagent, 100 Determinations","description":"Intended for quantitative determination of 25 OH Vitamin D in human serum or plasma using Access analyzers. Supports accurate vitamin D deficiency assessment.","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011562228,"sku":"B24838","price":397.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_ea6fd634-b1d0-4366-b4c8-1fdc5d9f4ee4.jpg?v=1774698454"},{"product_id":"beckman-coulter-b24839-access-25oh-vitamin-d-calibrators","title":"Beckman Coulter B24839 Access 25OH Vitamin D Calibrators","description":"Beckman Coulter B24839 Access 25OH Vitamin D Calibrator (Hydroxy Vitamin D) Specifications: Brand: Access 25 (OH) Vitamin D Manufacturer: Beckman Coulter B24839 Country of Origin: United States Application: Calibrator Container Type: Vial For Use With: For Access 2 Immunoassay Systems Form: Ready-To-UseLevels: 6 Levls Test Name: Total 25-Hydroxy Vitamin D (25OH Vitamin ) Test Type: Immunoassay \/ Nutritional Assessment INTENDED USE Total 25-Hydroxy Vitamin D Calibrator (25OH Vitamin ) The Access 25(OH) Vitamin D Total Calibrators are intended to calibrate the Access 25(OH) Vitamin D Total assay for the quantitative determination of total 25-hydroxyvitamin D [25(OH)D] levels in human serum and plasma using the Access 2 Immunoassay Systems. Results are to be used as an aid in the assessment of vitamin D sufficiency. SUMMARY AND EXPLANATION Total 25-Hydroxy Vitamin D Calibrator (25OH Vitamin ) Quantitative assay calibration is the process by which samples with known analyte concentrations (i.e., assay calibrators) are tested like patient samples to measure the response. The mathematical relationship between the measured responses and the known analyte concentrations establishes the calibration curve. This mathematical relationship, or calibration curve, is used to convert Relative Light Unit (RLU) measurements of patient samples to specific quantitative analyte concentrations.","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011594996,"sku":"B24839","price":208.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_3ac8f9bb-f8c3-488c-97c9-85bf9df85151.jpg?v=1774698456"},{"product_id":"beckman-coulter-33200-access-cea-reagent-100-determinations","title":"Beckman Coulter 33200 Access CEA Reagent, 100 determinations","description":"\u003cp\u003eIntended for quantitative measurement of CEA. Reagent supports clinical cancer marker evaluation.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011824372,"sku":"33200","price":320.9,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_c4987f5b-96a0-455a-a38d-f6fa996dca4d.jpg?v=1774698459"},{"product_id":"beckman-coulter-33205-access-cea-calibrator-s0-s5","title":"Beckman Coulter 33205 Access CEA Calibrator (S0-S5)","description":"Beckman Coulter 33205 Access CEA Calibrator (S0-S5) for Tumor Markers Assay Carcinoembryonic Antigen Test Specifications: Brand: Access Manufacturer: Beckman Coulter 33205 Country of Origin: Frane Application: Access CEA Calibrator Test Name: Carcinoembryonic Antigen Test (CEA) Test Type: Tumor Marker Assay Volume: 6 X 2.5mL Related products: 1.Beckman Coulter 33206 Access CEA Diluent 2.Beckman Coulter 33200 Access CEA Reagent, 100 determinations Beckman Coulter 33205 Data Sheet INTENDED USE: Beckman Coulter 33205 Access CEA Calibrator (S0-S5) for Tumor Markers Assay Carcinoembryonic Antigen Test The Access CEA Calibrators (BSA matrix) are intended to calibrate the Access CEA assay for the quantitative determination of Carcinoembryonic Antigen (CEA) levels in human serum, using the Access Immunoassay Systems. SUMMARY AND EXPLANATION: Beckman Coulter 33205 Access CEA Calibrator (S0-S5) for Tumor Markers Assay Carcinoembryonic Antigen Test Quantitative Tumor Marker Assay calibration utilizing the Access CEA calibrator is the process by which samples with known analyte concentrations (i.e. assay calibrators) are tested like patient samples to measure the response. The mathematical relationship between the measured responses and the known analyte concentrations establishes the calibration curve. The mathematical relationship or calibration curve is used to convert RLU (relative light units) measurements of patient samples to specific quantitative analyte concentrations. What are tumor marker tests (Carcinoembryonic Antigen Test)? These tests look for tumor markers, which are sometimes called cancer markers. Tumor-markers are substances that are often made by cancer cells or by normal cells in response to cancer. For example, some tumor markers are proteins that certain cancer cells make in larger amounts than normal cells do. Changes in the genes and other parts of tumor cells can be tumor markers, too. Certain tumor markers may be found in samples of body fluids, such as blood or urine (pee). Other tumor markers are found in samples of cells that are removed from a tumor during a biopsy. Tumor marker tests are mainly used after you have a cancer diagnosis. The test results may help answer important questions about your cancer, such as: How fast is the cancer growing? What type of treatment is most likely to help? Is the treatment really working? Has cancer come back after treatment? Not all cancers have known tumor-markers. And the tumor-markers that are known don't provide perfect information. That's because: Some conditions that aren't cancer may also cause high levels of certain tumor markers. Tumor marker tests can't tell whether tumor markers come from cancer or from another condition. Some people don't make high levels of the tumor markers that are commonly found in their type of cancer. But even with these limits, tumor marker testing can often give a more complete picture of your cancer when they are used along with the results of other tests and exams. What are they used for? [caption id=\"attachment_20669\" align=\"alignleft\" width=\"401\"] Beckman Coulter 33205 Access CEA Calibrator (S0-S5) for Tumor Markers Assay Carcinoembryonic Antigen Test[\/caption] Tumor marker tests are mainly used to learn more about a known cancer. But in certain cases, they may be used to screen for cancer or to help diagnose the disease. Tumor marker tests are most often used after you have a cancer diagnosis. When used with other tests, tumor markers may help: Find out whether cancer has spread to other parts of your body (cancer stage) Predict how fast your cancer may grow, the chance of recovery, and whether cancer is likely to return Select the right treatment for your type of cancer. Some treatments work only with cancers that have certain tumor markers. Tumor markers that help plan treatment are also called biomarkers.     Monitor how well your treatment is working. If tumor marker levels go down, it usually means your treatment is helping. Find any cancer that remains after treatment or cancer that comes back after treatment.","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682011857140,"sku":"33205","price":48.7,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_6f89ac0b-1a7d-4722-9f88-5b14758d4208.jpg?v=1774698461"},{"product_id":"beckman-coulter-33206-access-cea-diluent","title":"Beckman Coulter 33206 Access CEA Diluent","description":"\u003cp\u003eIntended for CEA assay dilution. 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Measurement of CRP is useful for the detection and evaluation of infection, tissue injury, inflammatory disorders and associated diseases. Measurements may also be useful as an aid in the identification of individuals at risk for future cardiovascular disease. High sensitivity CRP (hsCRP) measurements, when used in conjunction with traditional clinical laboratory evaluation of acute coronary syndromes, may be useful as an independent marker of prognosis for recurrent events, in patients with stable coronary disease or acute coronary syndromes. About Beckman Coulter OSR6199 C-reactive protein High sensitive CRP C-reactive protein (CRP) is one of the most sensitive acute-phase reactants. With the Beckman Coulter AU System CRP Latex reagent, CRP can be measured down to very low concentrations. Depending on the application used (different instrument settings) two measuring ranges are available: 1. Normal Application (1.0 - 480 mg\/L): C-reactive protein levels in serum can rise dramatically after myocardial infarction, stress, trauma, infection, inflammation, surgery, or neoplastic proliferation. The increase occurs within 24 to 48 hours, and the level may be 2000 times normal. Because the increase is non-specific, however, it cannot be interpreted without a complete clinical history, and even then only by comparison with previous values. 2. Highly Sensitive (Cardiac \/ Neonatal) Application – Beckman Coulter AU400\/400e\/480, AU600\/640\/640e\/680 (0.2 - 160 mg\/L), AU2700\/5400(0.2 – 80 mg\/L): C-reactive protein High sensitive CRP Studies: Studies have also shown that the detection of much lower CRP levels can provide valuable information. The typical CRP concentration for healthy adults is (depending on the specific level of the individual patient) \u0026lt; 1 mg\/L. Slightly higher values can indicate an increased risk for coronary heart disease in asymptomatic patients. CRP concentrations above 3 mg\/L, at the time of hospital admission, predict a precarious outcome after a myocardial infarct. The following relative risk categories in relation to average CRP level have been recommended: Low \u0026lt; 1mg\/L, Average 1.0 to 3.0 mg\/L and High \u0026gt; 3.0 mg\/L. Increases in C-Reactive Protein values are not specific and should not be interpreted without a complete clinical history since CRP is an acute phase protein which can rise non-specifically due to other inflammatory conditions. For cardiac risk analysis, other cardiac disease-specific testing must be done, such as Total cholesterol, HDL cholesterol, and LDL cholesterol. When being used for risk assessment, levels of CRP \u0026gt; 10 mg\/L should be evaluated for other non-cardiovascular origins. Testing for any risk assessment should not be performed while there is indication of infection, systemic inflammation, or trauma. This assay is not meant for management of acute coronary syndrome and is not a substitute for traditional cardiovascular risk factors. Screening the entire adult population for hsCRP is not recommended. The average of hsCRP levels determined two weeks apart should be used in performing risk assessment on metabolically stable patients. hsCRP is considered to be a Class IIa marker for acute coronary syndrome in addition to Troponin I. Cord blood normally has very low CRP concentrations (median 0.12 mg\/L). In the diagnostic evaluation of neonates with suspected infection, measurements of serial CRP levels are useful. Two low CRP levels obtained 24 hours apart indicate that bacterial infection is highly unlikely. Thus, CRP Latex reagent is a valuable tool for the early diagnosis of infection in preterm infants and neonates. It assesses both the need for, and the effectiveness of, antibiotic treatment. However, CRP values alone should not be used as a basis for early discontinuance of antibiotic therapy. Beckman Coulter OSR6199 C-reactive Protein High sensitive CRP: Methodology Immune complexes formed in solution scatter light in proportion to their size, shape, and concentration. Turbidimeters measure the reduction of incidence light due to reflection, absorption, or scatter. In this procedure, the measurement of the rate of decrease in light intensity transmitted (increase in absorbance) through particles suspended in solution is the result of complexes formed during the immunological reaction between the CRP of the patient serum and rabbit anti-CRP-antibodies coated on latex particles.","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682012479732,"sku":"OSR6199","price":522.3,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_b982b910-3d92-43cf-80ce-558a18211ac0.jpg?v=1774698470"},{"product_id":"beckman-coulter-osr6119-olympus-ggt-reagent-r1-4x310-tests","title":"Beckman Coulter OSR6119 Olympus GGT Reagent R1 (4x310 tests)","description":"\u003cp\u003eIntended for measurement of gamma-glutamyl transferase (GGT) in serum or plasma. 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Ensures precise clinical measurement of folate levels.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682012872948,"sku":"A98033","price":152.3,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_7cb91deb-9350-46cd-8e6b-684a73bb99c7.jpg?v=1774698495"},{"product_id":"beckman-coulter-33550-access-progesterone-reagent-100-determinations","title":"Beckman Coulter 33550 Access Progesterone Reagent, 100 Determinations","description":"Beckman Coulter 33550 Access Progesterone Reagent Specifications: Brand: Access Manufacturer: Beckman Coulter 33550 Country of Origin: United State Application: Reagent, Rental Progesterone Reagent Number of Tests: 100 Tests Test Name: Progesterone Test Type: Reproductive Endocrinology Asya Beckman Coulter 33550 Access Progesterone Reagent: INTENDED USE The Access Progesterone assay, made of Beckman Coulter 33550 Access Progesterone Reagent is a paramagnetic particle, chemiluminescent immunoassay for the quantitative determination of progesterone levels in human serum using the Access Immunoassay Systems. Beckman Coulter 33550 Access Progesterone Reagent: SUMMARY AND EXPLANATION Physiological occurrence Both men and women produce low levels of progesterone, a steroid hormone in the adrenal cortex. Progesterone is important, not only as a hormone, but also as the precursor of the estrogens, androgens, and adrenocortical steroids.In women, during the follicular phase of the menstrual cycle, serum levels remain low. After ovulation, there is a significant rise in serum levels when the corpus luteum begins to produce progesterone in increasing amounts. This causes changes in the uterus, preparing it for implantation of a fertilized egg. Beckman Coulter 33550 Access Progesterone Reagent: More about implantation If implantation occurs, the trophoblast begins to secrete hCG (human chorionic gonadotropin), which maintains the corpus luteum and its secretion of progesterone. By the end of the first trimester, the placenta becomes the primary secretor, and serum levels continue to increase. If there is no implantation, the corpus luteum degenerates and circulating progesterone levels decrease rapidly, reaching follicular phase levels about 4 days before the next menstrual period.Metabolism and transportSteroid syntheses begin with acetate conversion pathways to cholesterol. Beckman Coulter 33550 Access Progesterone Reagent: metabolites of progesterone Pregnenolone is the immediate precursor and 17-? hydroxyprogesterone one of the first metabolites of progesterone.The predominant metabolite in the liver is pregnanediol, generally as a water soluble sulfate or glucuronide, which can then be secreted by the kidneys. Progesterone is transported mainly through binding to albumin, and to a lesser extent corticosteroid binding globulin (CBG) or sex hormone binding globulin (SHBG).Clinical applicationsIn general, increasing progesterone levels are indicative of viable pregnancies. Ultrasonography is required to confirm viability at low progesterone levels. Serum concentrations are relatively constant at 8-10 weeks gestation, unless the pregnancy is failing, which can be signaled by decreasing progesterone values. After 10-12 weeks, levels increase more rapidly, but serum progesterone determinations are not considered useful for diagnoses in late pregnancy.Ovulation, and the presence of a functioning corpus luteum, can be demonstrated with serial determinations of serum progesterone. Luteal phase dysfunction may be diagnosed when ovulation has occurred and there is inadequate luteinization and reduced progesterone secretion.","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682013135092,"sku":"33550","price":154.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_7fec8e58-3c62-4c8e-ac9b-9ccfba659725.jpg?v=1774698497"},{"product_id":"beckman-coulter-33560-access-testosterone-reagent","title":"Beckman Coulter 33560 Access Testosterone Reagent","description":"\u003cp\u003eIntended for quantitative measurement of testosterone. Reagent supports clinical and endocrinology testing.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682013233396,"sku":"33560","price":136.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_090e396d-cc8a-443c-8ed0-e1f2ee5db0be.jpg?v=1774698500"},{"product_id":"beckman-coulter-33565-testosterone-calibrator","title":"Beckman Coulter 33565 Testosterone CalIbrator","description":"\u003cp\u003eIntended for calibration of testosterone assays. Ensures precise hormone quantification.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682013462772,"sku":"33565","price":61.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_06776f5b-f9b9-45c7-9c86-19f2b4d0ef97.jpg?v=1774698502"},{"product_id":"beckman-coulter-a10826-access-dhea-s-reagent-100-determinations","title":"Beckman Coulter A10826 Access DHEA-S Reagent, 100 Determinations","description":"\u003cp\u003eIntended for quantitative measurement of DHEA-S. Reagent supports endocrine function evaluation.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682013495540,"sku":"A10826","price":121.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_4072b4c9-6f0f-42e9-babb-e5305b7a2457.jpg?v=1774698504"},{"product_id":"beckman-coulter-a10827-access-dheas-calibrator-s0-s5","title":"Beckman Coulter A10827 Access DHEAS Calibrator (S0-S5)","description":"\u003cp\u003eIntended for calibration of DHEAS assays. Ensures accurate adrenal and endocrine assessment.\u003c\/p\u003e","brand":"Beckman Coulter","offers":[{"title":"Default Title","offer_id":47682013724916,"sku":"A10827","price":91.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/files\/JIT_Beckman_5e9a2d24-573f-4a7a-aee8-2e011c9334a9.jpg?v=1774698506"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9256\/7796\/collections\/JIT_Beckman_4c746ffc-c07b-44d7-89e3-b73dc486ba55.jpg?v=1781085076","url":"https:\/\/jit4labs.com\/collections\/beckman-coulter-analyser-hub.oembed?page=5","provider":"jit4labs","version":"1.0","type":"link"}